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Skip to main content Thank you for visiting nature. Abstract Simian virus 40 SV40 and SV40 T tumour antigen have been detected in the malignant melanoma metastases of a patient in which specific viral and T antibodies were demonstrated. Access through your institution. Buy or subscribe. This is a preview of subscription content. Change institution. Buy article Get time limited or full article access on ReadCube.
References 1 Melnick, J. Google Scholar 3 Rapp, F. Google Scholar 4 Granboulan, N. Article Google Scholar 6 Kirchstein, R. Google Scholar 7 Del Villano, B. View author publications. Rights and permissions Reprints and Permissions.
About this article Cite this article Soriano, F. Copy to clipboard. Suzuki Masahiro Mizoguchi Toru Iwaki Brain Tumor Pathology Failure to detect viral genomic sequences of three viruses herpes simplex, simian virus 40 and adenovirus in human and rat brain tumors C.
Chauvin M. Cancer Biol. Jha, K. Banga, V. Palejawala, and H. SVmediated immortalization. Cell Res. Khoury, G. Regulation of early and late simian virus 40 transcription: overproduction of early viral RNA in the absence of a functional T-antigen.
Kim, J. Koralnik, M. LeFave, R. Segal, L. Pfister, and S. Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences. Kirschstein, R. Ependymomas produced after intracerebral inoculation of SV40 into new-born hamsters. Nature : Klein, G. Powers, and C. Oncogene 21 : Koprowski, H. Ponten, F. Jensen, R. Ravdin, P. Moorhead, and E. Transformation of cultures of human tissue infected with simian virus Kouhata, T.
Fukuyama, N. Hagihara, and K. Detection of simian virus 40 DNA sequence in human primary glioblastomas multiforme. Krainer, M. Schenk, C. Zielinski, and C. Failure to confirm presence of SV40 sequences in human tumors. Cancer 31 : Krieg, P. Antmann, D. Jonas, H. Fischer, K. Zang, and G. Episomal simian virus 40 genomes in human brain tumors. USA 78 : Cloning of SV40 genomes from human brain tumors. Virology : Krynska, B. Valle, S. Croul, J.
Gordon, C. Katsetos, M. Carbone, A. Giordano, and K. Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas. USA 96 : Laghi, L.
Randolph, D. Chauhan, G. Marra, E. Neel, and C. JC virus DNA is present in the mucosa of the human colon and in colorectal cancers. Lane, D. T antigen is bound to a host protein in SVtransformed cells. Lednicky, J. Raptis ed. Humana Press, Totowa, N. Garcea, D. Bergsagel, and J. Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors.
Stewart, J. Jenkins, M. Finegold, and J. Cancer 72 : The tumor suppressor genes. Li, R. Branton, S. Tanawattanacharoen, R. Falk, J. Jennette, and J. Molecular identification of SV40 infection in human subjects and possible association with kidney disease. Linzer, D. Characterization of a 54K dalton cellular SV40 tumor antigen present in SVtransformed cells and uninfected embryonal carcinoma cells.
Cell 17 : Malkin, D. Chilton-MacNeill, L. Meister, E. Sexsmith, L. Diller, and R. Tissue-specific expression of SV40 in tumors associated with the Li-Fraumeni syndrome.
Oncogene 20 : Martinelli, M. Martini, E. Rinaldi, L. Caramanico, E. Magri, E. Grandi, F. Carinci, A. Pastore, and M. Simian virus 40 sequences and expression of the viral large T antigen oncoprotein in human pleomorphic adenomas of parotid glands. Martini, F. Iaccheri, L. Lazzarin, P. Corallini, M. Gerosa, P. Iuzzolino, G. Barbanti-Brodano, and M. SV40 early region and large T antigen in human brain tumors, peripheral blood cells, and sperm fluids from healthy individuals. McCormick, F. Association of a murine 53,dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells.
Meinke, W. Goldstein, and R. Simian virus related DNA sequences in a human brain tumor. Neurology 29 : Melnick, J. Excretion of vacuolating SV virus papova virus group after ingestion as a contaminant of oral poliovaccine. Mendoza, S. Konishi, and C. Oncogene 17 : Monaco, M. Jensen, J. Hou, L. Durham, and E. Shin, and E. JC virus infection in cells from lymphoid tissue.
Monini, P. Rotola, D. Di Luca, L. De Lellis, E. Chiari, A. Corallini, and E. DNA rearrangements impairing BK virus productive infection in urinary tract tumors. Morris, J. Johnson, C. Aulisio, R. Chanock, and V. Clinical and serological responses in volunteers given vacuolating virus SV40 by respiratory route. Mortimer, E. Lepow, E. Gold, F.
Robbins, G. Burton, and J. Long-term follow-up of persons inadvertently inoculated with SV40 as neonates. Murakami, Y. Weissbach, F. Dean, and J. USA 83 : Pacini, F. Vivaldi, M. Santoro, M. Fedele, A. Fusco, C. Romei, F. Basolo, and A. Simian virus like DNA sequences in human papillary thyroid carcinomas. Oncogene 16 : Padgett, B. New human papovaviruses. Prevalence of antibody in human sera against JC virus, an isolate from a case of progressive multifocal leukoencephalopathy.
Walker, G. ZuRhein, R. Eckroade, and B. Cultivation of a papova-like virus from human brain with progressive multifocal leukoencephalopathy. Pagano, J. Viruses and lymphoma. Pallas, D.
Shahrik, B. Martin, S. Jaspers, T. Miller, D. Brautigan, and T. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell 60 : Ponten, J. Morphological and virological investigation of human tissue cultures transformed with SV Porcu, P.
Ferber, Z. Pietrzkowski, C. Roberts, M. Adamo, D. LeRoith, and R. The growth-stimulatory effect of simian virus 40 T antigen requires the interaction of insulin-like growth factor 1 with its receptor. Porras, A. Gaillard, and K. The simian virus 40 small-t and large T antigens jointly regulate cell cycle reentry in human fibroblasts. Portolani, M. Borgatti, A. Corallini, E. Cassai, M. Grossi, and G. Stable transformation of mouse, rabbit, and monkey cells and abortive transformation of human cells by BK virus, a human papovavirus.
Rabson, A. O'Connor, L. Kirschstein, and W. Papillary ependymomas produced in Rattus mastomys natalensis inoculated with vacuolating virus SV Ray, G.
Peabody, J. Cooper, L. Cram, and P. SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts. Reed, S. Ferguson, R. Davis, and C. T antigen binds to simian virus 40 DNA at the origin of replication. USA 72 : Stark, and J. Autoregulation of simian virus 40 gene A by T antigen. USA 73 : Carbone, S. Fisher, C. Matker, L. Swinnen, A.
Powers, I. Di Resta, S. Alkan, H. Pass, and R. Simian virus 40 is present in most United States human mesotheliomas, but it is rarely present in non-Hodgkin's lymphoma.
Chest : SS. Rundell, K. The role of the SV40 ST antigen in cell growth promotion and transformation. Saenz-Robles, M. Sullivan, and J. Transforming functions of simian virus Schell, T. Cytotoxic T lymphocytes in SV40 infections. Methods Mol. Scherneck, S. Rudolph, E. Geissler, F. Vogel, L. Lubbe, H. Wahlte, G.
Nisch, F. Weickman, and W. Isolation of an SV like papovavirus from human glioblastoma. Cancer 24 : Sepulveda, A. Finegold, B. Smith, B. Slagle, J. DeMayo, R. Shen, S. Woo, and J. Shah, K. Human exposure to SV review and comment. Does SV40 infection contribute to the development of human cancers?
Shein, H. Multiplication and cytopathogenicity of simian vacuolating virus 40 in cultures of human tissues. Enders, and J. Transformation induced by simian virus 40 in human renal cell cultures. Cell-virus relationships. USA 48 : Shivapurkar, N.
Harada, J. Reddy, R. Scheuermann, Y. Xu, R. McKenna, S. Milchgrub, S. Kroft, Z. Feng, and A. Presence of simian virus 40 DNA sequence in human lymphomas. Lancet : Wiethege, I. Wishuba, E. Salomon, S. Devesa, et al. Vilchez, R. Arrington, and J. Materials in this section are updated as new information and vaccines become available. The Vaccine Education Center staff regularly reviews materials for accuracy.
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However, several facts should be noted: SV40 was present in cancers of people who either had or had not received the polio vaccines that were contaminated with SV SV40 has not been present in any vaccine since People with cancers who were born after , when SV40 was no longer a contaminant of the polio vaccine, were found to have evidence for SV40 in their cancerous cells. Epidemiologic studies do not show an increased risk of cancers in those who received polio vaccine between and References Carroll-Pankhurst, C.
Ferber D. Monkey virus links to cancer grow stronger.
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